ARG30131

Postsynaptic Receptor Antibody Panel (NMDAR2A, NMDAR2B, GluR1)

Datasheet

参考文献4

订购信息

包装

价格 (USD)

1 kit

937

arigo in CHINA:
恩瑞科生物
☎ 400-886-0853,
0571-8708-1890

内含物

货号	内含物名称	宿主克隆性	反应	应用	包装
ARG52358	anti-NMDAR2A antibody	Rabbit pAb	Ms, Rat, Rb	IHC-Fr, WB	50 μl
ARG52363	anti-NMDAR2B antibody	Rabbit pAb	Ms, Rat	WB	50 μl
ARG52314	anti-GluR1 antibody [RH95]	Mouse mAb	Ms, Rat	WB	50 μl
ARG65350	Goat anti-Mouse IgG antibody (HRP)	Goat pAb	Ms	ELISA, IHC-P, WB	50 μl
ARG65351	Goat anti-Rabbit IgG antibody (HRP)	Goat pAb	Rb	ELISA, IHC-P, WB	50 μl

概述

产品描述	Synaptic plasticity, the variable efﬁcacy of neurotransmission at synapses, is thought to form the memories. Glutaminergic synapses mediate virtually all excitatory neurotransmission in mammalian brains. Glutamate released from presynaptic terminals activates several types of glutamate-gated ion channels on postsynaptic membranes, including a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, consist of subunits GluR1-GluR4, and N-methyl-D-aspartate (NMDA) receptors. Changes in AMPA receptors at the postsynaptic membrane cause changes in synaptic strength, the best-characterized forms of which are long-term potentiation (LTP) and long-term depression (LTD). This antibody panel could be used to investigate the ratio of NMDAR to AMPAR or the change of AMPAR on the postsynaptic membrane. During the LTP, the AMPARs increase expression on the membrane of post-synapse, and the ratio of NMDAR to AMPAR would be higher than the pre-LTP. In construct, LTD decreases the AMPARs expression, and the ratio would be lower than pre-LTD.
靶点名称	Postsynaptic Receptor
別名	Postsynaptic Receptor antibody; GluR1 antibody; NMDAR2A antibody; NMDAR2B antibody

属性

存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名	Antibody Panel for Postsynaptic Receptor (NMDAR2A, NMDAR2B, GluR1)
产品亮点	Related Product: anti-NMDAR2A antibody; anti-NMDAR2B antibody; anti-GluR1 antibody;
研究领域	Immune System antibody; Neuroscience antibody

检测图片 (10) Click the Picture to Zoom In

ARG65351 Goat anti-Rabbit IgG antibody (HRP) IHC-P image

From Yu-Qian Song et al. J Mol Med (Berl) (2022), doi: 10.1007/s00109-021-02165-0, Fig. 5.c.
ARG65351 Goat anti-Rabbit IgG antibody (HRP) WB image

Western blot: HK2 stained with ARG66421 anti-CXCL12 / SDF1 antibody [SQab18123] and ARG10112 anti-GAPDH antibody [6C5] and secondary antibody used ARG65351 Goat anti-Rabbit IgG antibody (HRP).

From Zhou Y et al. Central European Journal of Immunology (2022), doi: 10.5114/ceji.2022.115628, Fig. 2. E.
ARG52358 anti-NMDAR2A antibody WB image

Western Blot: 10 µg of Rat hippocampal (Hipp) lysate stained with ARG52358 anti-NMDAR2A antibody showing specific immunolabeling of the ~180 kDa NR2A subunit of the NMDA receptor.
ARG52314 anti-GluR1 antibody [RH95] WB image

Western Blot: rat hippocampal lysate showing specific immunolabeling of the ~105k GluR1 protein stained with GluR1 antibody (ARG52314).
ARG52363 anti-NMDAR2B antibody WB image

Western blot: 10 ug of rat hippocampal (Hipp) lysate stained with ARG52363 anti-NMDAR2B antibody showing specific immunolabeling of the ~180k NR2B subunit of the NMDA receptor.
ARG52358 anti-NMDAR2A antibody IHC-Fr image

Immunohistochemistry: Rabbit retina stained with ARG52358 anti-NMDAR2A antibody showing NR2A in the rod and cone photoreceptors in the outer plexiform layer as well as the entire inner plexiform layer.
ARG65350 Goat anti-Mouse IgG antibody (HRP) IHC-P image

From Cheng-Feng Chu et al. J Pers Med. (2021), doi: 10.3390/jpm11121326, Fig. 6.
ARG65350 Goat anti-Mouse IgG antibody (HRP) WB image

Western blot: Neuro-2a stained with ARG22361 anti-Aquaporin 4 antibody , ARG40638 anti-MMP9 antibody and ARG65350 Goat anti-Mouse IgG antibody (HRP).

From Hung CY et al. Molecules (2022), doi: 10.3390/molecules27031066, Fig. 6A.
ARG65350 Goat anti-Mouse IgG antibody (HRP) WB image

Western blot: Rat basolateral amygdala stained with ARG62347 anti-beta Tubulin antibody [BT7R] at 1:1000 dilution, ARG65350 Goat anti-Mouse IgG antibody (HRP) at 1:5000 dilution.

From Guang-Bing Duan et al. CNS Neurosci Ther. (2024), doi: 10.1111/cns.14611, Fig. 4.D.
ARG65351 Goat anti-Rabbit IgG antibody (HRP) WB image

Western blot: Gastric cancer cells stained with ARG66247 anti-Bax antibody, ARG55188 anti-Bcl 2 antibody, ARG57512 anti-Caspase 3 (cleaved) antibody and ARG62346 anti-beta Actin antibody [BA3R].
Secondary Antibody stained with ARG65351 Goat anti-Rabbit IgG antibody (HRP).

From Limin Zhang et al. Heliyon (2024), doi: 10.1016/j.heliyon.2024.e30803, Fig. 4. C.