ARG22104

anti-Ly6G + Ly6C antibody [RB6-8C5]

anti-Ly6G + Ly6C antibody [RB6-8C5] for Depletion,Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,IHC-Frozen sections,Immunoprecipitation and Mouse

概述

产品描述 Rat Monoclonal antibody [RB6-8C5] recognizes Ly6G + Ly6C
反应物种 Ms
应用 Depletion, FACS, IHC-Fr, IHC-P, IP
特异性 This antibody recognizes the mouse Gr-1 antigen, a ~21 - 25 kDa GPI anchored cell surface protein bearing a single uPAR/Ly6 domain that belongs to the Ly-6 family of proteins (Lee et al. 2013). Clone RB6-8C5 reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been reported (Fleming et al. 1993). However, other observations dispute the cross-reactivity of clone RB6-8C5 with the Ly-6C protein with the alternative explanation that certain sub-populations of bone marrow cells simultaneously express both Ly-6C and Ly-6G (Nagendra et al. 2007).
宿主 Rat
克隆 Monoclonal
克隆号 RB6-8C5
同位型 IgG2bκ
靶点名称 Ly6G + Ly6C
抗原物种 Mouse
偶联标记 Un-conjugated
全名 lymphocyte antigen 6 complex, locus G
別名 Gr1; Gr-1; Ly-6G

应用说明

应用建议
应用 推荐稀释比
DepletionAssay-dependent
FACSAssay-dependent
IHC-FrAssay-dependent
IHC-PAssay-dependent
IPAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
缓冲液 BBS (pH 8.2)
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 546644 Mouse Ly6g

基因名称 Ly6g
基因全名 lymphocyte antigen 6 complex, locus G
背景介绍 Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses. _x000D_

检测图片 (1) Click the Picture to Zoom In

  • ARG22104 anti-Ly6G + Ly6C antibody [RB6-8C5] IHC-Fr image

    Immunohistochemistry: Mouse spleen section stained with ARG22104 anti-Ly6G + Ly6C antibody [RB6-8C5] followed by ARG21706 Mouse anti-Rat IgG2b antibody [2B10A8] (FITC).