ARG30336

Human MDSC Marker Antibody Duo

Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells
publication_link 参考文献4

内含物

货号 内含物名称 宿主克隆性 反应 应用 包装
ARG22000 anti-CD11b antibody [M1/70] Rat mAb Hu, Ms, Bb, R. Mk BL, FACS, ICC/IF, IHC-Fr, IP 50 μg
ARG65560 anti-CD33 antibody [WM53] Mouse mAb Hu, NHuPrm CyTOF®-candidate, FACS, FuncSt, ICC/IF, IHC-Fr, IP, WB 50 μg

概述

产品描述 Human MDSC Marker Antibody Duo includes antibodies to MDSC marker, CD11b and CD33, for Myeloid-derived suppressor cells (MDSCs) study. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immune cells from the myeloid lineage. MDSCs are well-known key negative regulators of the immune response in tumor microenvironment. Accumulated evidences show that MDSCs may serve as a therapeutic target for preventing tumor progression.In humam, MDSCs are defined as cells expressing CD33 and CD11b. arigo’s Human MDSC Marker Antibody Duo comprises CD33 and CD11b antibodies. It is the best solution to identify the MDSCs in human tumor tissues.

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靶点名称 Human MDSC marker
別名 Human MDSC Marker antibody; Myeloid-derived suppressor cells marker antibody; MDSCs marker antibody; CD11b antibody; CD33 antibody

属性

存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名 Human Myeloid-derived suppressor cell (MDSC) marker Antibody Duo
产品亮点 Related products:
MDSC Duos / Panels;
研究领域 Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells

检测图片 (5) Click the Picture to Zoom In

  • ARG65560 anti-CD33 antibody [WM53] IHC-Fr image

    Immunohistochemistry: Frozen section of Human colon tissue stained with ARG65560 anti-CD33 antibody [WM53].

  • ARG22000 anti-CD11b antibody [M1/70] IHC-Fr image

    Immunohistochemistry: Cryosection of Mouse lymph node stained with ARG22000 anti-CD11b antibody [M1/70] (green, A) and anti-Mouse CD8 antibody (red, B). Merged image in C.

  • ARG65560 anti-CD33 antibody [WM53] CyTOF image

    CyTOF: Human peripheral blood stained with ARG65560 anti-CD33 antibody [WM53] (149Sm). Singlet cells were gated for data analysis.

  • ARG65560 anti-CD33 antibody [WM53] FACS image

    Flow Cytometry: Separation of Human CD33 positive Monocytes (red) from Human CD33 negative Lymphocytes (black-dashed). Human peripheral blood stained with ARG65560 anti-CD33 antibody [WM53], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.

  • ARG65560 anti-CD33 antibody [WM53] FACS image

    Flow Cytometry: PBMC stained with ARG65560 anti-CD33 antibody [WM53] at 0.5 µg/10^6 cells (right histogram) or isotype control (left histogram), followed by incubation with PE labelled secondary antibody.

文献引用

Acupuncture promotes neurological recovery and regulates lymphatic function after acute inflammatory nerve root injury

ARG22000: IHC-Fr / Human

Jie Wang et al.
Heliyon.,  (2024)

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Mac-1 deficiency ameliorates pressure overloaded heart failure through inhibiting macrophage polarization and activation

ARG22000: IHC-Fr, WB / Mouse

Qiu-Yue Lin et al.
BBA - Molecular Basis of Disease,  (2024)

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Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration

ARG22000:WB / Mouse

Qiu-Yue Lin et al.
Hypertension.,  (2023)

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CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization

Mouse / ARG22000: IHC-P, WB

Yun-Long Zhang et al.
J Adv Res.,  (2023)

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