Senescence Marker Antibody Panel is launched

Senescence Marker Antibody Panel is launched



Senescence is a state of permanent cell cycle arrest. It can be induced by telomere shortening, DNA damages or other cellular stresses. Senescence has been implicated as a major cause of age-related diseases and believed to prevent cancer progression. arigo offers a series of antibodies and ELISA kits to facilitate the characterization of cellular senescence.

► Cell cycle arrest (SAGA)

Senescence Marker Antibody Panel (ARG30340)

● Includes antibodies for studying p16 INK4a-Rb pathway
● Includes antibodies for studying p53-p21 pathway
● Works on human, mouse, and rat samples

Component Reactivity Application
p16 INK4a antibody Hu, Ms, Rat ICC/IF, IP, WB
Rb pSer807 antibody Hu, Ms, Rat IHC-P, WB
p53 antibody [Pab1801] Hu, Ms, Rat ChIP, ELISA, FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB
p21 antibody Hu, Ms, Rat ICC/IF, WB


► Senescence-associated Heterochromatin Foci (SAHF)

Heterochromatin Foci Antibody Duo (ARG30341)

● Includes H3K9me2 and HP1 gamma antibodies
● Outstanding ICC and IHC performance
● Works on human, mouse, and rat samples



► DNA damage & Loss of Lamin B1

gamma H2A.X antibody (ARG55251)

Reactivity: Hu, Ms
Application: ICC/IF, WB

Lamin B1 antibody (ARG65740)

Reactivity: Hu, Ms, Rat
Application: ICC/IF, IHC-P, WB


► SA-beta-Gal activity

Cellular Senescence Assay Kit (ARG82213)

● Ideal for quantification of senescence
● Efficiently detect SA-β-Gal activity from lysates
● Easy-to-use procedure with results within 1~3 hrs
● Compatible with all cell types



► Senescence-associated Secretory Phenotype (SASP)

ELISK kit Human Mouse Rat
HMGB1 ARG81185 ARG81310 ARG81310
IL-1 alpha ARG80191 ARG80204 ARG80237
IL-6 ARG80110 ARG80199 ARG80233
IL-8 ARG80111    
CCL-2/MCP1 ARG80128 ARG80212 ARG80246
CXCL1 ARG81631 ARG80208 ARG80236
MMP-1 ARG80145 ARG82074 ARG82075
MMP-3 ARG81267 ARG81662 ARG82625