ARG65740

Name: anti-Lamin B1 antibody
Brand: arigo Biolaboratories
SKU: ARG65740
Price: 389 USD
Availability: InStock
Rating: 4.3 (3 reviews)

anti-Lamin B1 antibody

Datasheet

参考文献3

订购信息

包装

价格(USD)

100 μl

389

50 μl

272

arigo in CHINA:
恩瑞科生物
☎ 400-886-0853,
0571-8708-1890

概述

产品描述	Rabbit Polyclonal antibody recognizes Lamin B1
反应物种	Hu, Ms, Rat
应用	ICC/IF, IHC-P, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	Lamin B1
抗原物种	Human
抗原	Recombinant protein of Human Lamin B1
偶联标记	Un-conjugated
別名	LMN2; ADLD; Lamin-B1; LMN; LMNB

应用说明

应用建议

应用	推荐稀释比
ICC/IF	1:50 - 1:200
IHC-P	1:50 - 1:200
WB	1:500 - 1:2000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

阳性对照

Jurkat

属性

形式	Liquid
纯化	Affinity purification with immunogen.
缓冲液	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 116685 Rat LMNB1 GeneID: 16906 Mouse LMNB1 GeneID: 4001 Human LMNB1 Swiss-port # P14733 Mouse Lamin-B1 Swiss-port # P20700 Human Lamin-B1 Swiss-port # P70615 Rat Lamin-B1 More
基因名称	LMNB1
全名	lamin B1
背景介绍	The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010]
生物功能	Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. [UniProt]
产品亮点	Related products: Lamin B1 antibodies; Lamin B1 Duos / Panels; Anti-Rabbit IgG secondary antibodies;
研究领域	Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Controls and Markers antibody; Signaling Transduction antibody; NRF-2 Nuclear Localization Study antibody
预测分子量	66 kDa
翻译后修饰	B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations.

检测图片 (4) Click the Picture to Zoom In

ARG65740 anti-Lamin B1 antibody WB image

Western blot: 30 µg of Mouse spleen and Rat spleen lysates stained with ARG65740 anti-Lamin B1 antibody at 1:500 dilution.
ARG65740 anti-Lamin B1 antibody ICC/IF image

Immunofluorescence: U2OS cells stained with ARG65740 anti-Lamin B1 antibody.
ARG65740 anti-Lamin B1 antibody IHC-P image

Immunohistochemistry: Paraffin-embedded Human colon stained with ARG65740 anti-Lamin B1 antibody at 1:100 dilution.
ARG65740 anti-Lamin B1 antibody WB image

Western blot: Jurkat cell lysate stained with ARG65740 anti-Lamin B1 antibody.