Examining Neutrophil activity by multiplex ELISA kit
Examining Neutrophil activity by multiplex ELISA kit
Neutrophils are key mediators of acute inflammation, eliminating pathogens through phagocytosis, degranulation, and release of neutrophil extracellular traps (NETs). Emerging evidence suggests that neutrophils are involved in a range of chronic inflammatory diseases, including atherosclerosis, diabetes mellitus, nonalcoholic fatty liver disease, and autoimmune disorders. Understanding neutrophil activity is crucial for elucidating the pathophysiology of chronic inflammatory diseases and may open avenues for new therapeutic approaches targeting neutrophil functions.
arigo offers Human Neutrophil Activation Multiplex ELISA Kit (ARG83799) to facilitate the examination of neutrophil activity by quantifying 4 soluble neutrophil activity markers simultaneously.
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Benefits ● Concurrent measurement of 4 factors |
MPO: 125 pg/mL |
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MPO |
is an enzyme released by activated neutrophils. It produces reactive oxygen species (ROS) to destroy pathogens. However, MPO-derived ROS also contribute to tissue damage in various inflammatory diseases. |
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NE |
is a protease released by neutrophils that breaks down proteins in pathogens but can also damage host tissues. |
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IL-8 |
is the primary neutrophil chemoattractant. In addition to chemotaxis, IL-8 also induces degranulation and release of neutrophil extracellular traps (NETs), enhancing the ability to fight pathogens. |
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IL-6 |
is a pro-inflammatory cytokine with activity to promote neutrophil production, mobilization from the bone marrow, and survival. |
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▶ More Neutrophil research solutions
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▶ arigoPLEX® Multiplex ELISA Kits |
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