Inflammatory Chemokine Multiplex ELISA Kit for your research

Inflammatory Chemokine Multiplex ELISA Kit for your research


 

arigo is proud to introduce arigoPLEX® Human Inflammatory Chemokine Multiplex ELISA Kit which make the complex quantification of multiple chemokines easy and efficient. This kit is the best solution to monitor infections, autoimmune diseases, transplant rejection, and cancer progression.

 

Human Inflammatory Chemokine Multiplex ELISA Kit (ARG83673)

Benefits

●  Concurrent measurement of 4 chemokines
●  Quantifying at pg/mL ranges
●  Single detection reagent
●  Measured by ELISA reader at OD 450 nm

 

IL-8: 15.625 pg/mL
MCP-1: 15.625 pg/mL
RANTES: 15.625 pg/mL
IP-10: 31.25 pg/mL

 


 

Inflammatory chemokines function to recruit effector leucocytes in response to infection, inflammation, tissue injury, and tumors. These chemokines induce chemotaxis of neutrophils, monocytes, macrophages, and T cells. Inflammatory chemokines are involved in the inflammatory response, as well as participate in tumorigenesis and metastasis. Recent research has revealed that inflammatory chemokines are associated with neurological disorders such as anxiety, Alzheimer's disease (AD), and HIV-associated dementia (HAD).

 

IL-8 (CXCL8)

not only attracts and activates neutrophils but also promote angiogenesis and tumor invasion. Elevated IL-8 levels are strongly associated with inflammatory, infectious, and malignant conditions.

MCP-1 (CCL2)

is the key chemokine that regulate migration and infiltration of monocytes and macrophages. MCP-1 levels are associated with the severity of infection and diseases.

RANTES (CCL5)

is a chemoattractant for T cells, eosinophils, basophils, and monocytes. It is involved in antiviral responses and allergic reactions.

IP-10 (CXCL10)

is a chemokine secreted in response to IFN-γ for recruiting T cells, NK cells, dendritic cells, and monocytes/macrophages. It serves as a biomarker for T-cell mediated immune activation.

 


 

▶  arigoPLEX® Multiplex ELISA Kits

multiplex ELISA kit