ARG22372

anti-CD206 / MMR antibody

anti-CD206 / MMR antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Pig,Rat

Immune System antibody; M1/M2/TAM Marker antibody; Macrophage Marker antibody; M2 Macrophage Marker antibody
publication_link 参考文献2

概述

产品描述

Rabbit Polyclonal antibody recognizes CD206 / MMR

反应物种 Hu, Ms, Rat, Pig
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 CD206 / MMR
抗原物种 Human
抗原 KLH-conjugated synthetic peptide from Human CD206 / MMR.
偶联标记 Un-conjugated
全名 mannose receptor, C type 1
別名 CLEC13D; C-type lectin domain family 13 member D; Macrophage mannose receptor 1-like protein 1; C-type lectin domain family 13 member D-like; MMR; CLEC13DL; CD206; Macrophage mannose receptor 1; bA541I19.1; CD antigen CD206; MRC1L1

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:400
IHC-P1:100 - 1:500
WB1:300 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
预测分子量 166 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS and 0.02% Sodium azide.
抗菌剂 0.02% Sodium azide
浓度 0.5 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 17533 Mouse MRC1

GeneID: 4360 Human MRC1

Swiss-port # P22897 Human Macrophage mannose receptor 1

Swiss-port # Q61830 Mouse Macrophage mannose receptor 1

基因名称 MRC1
基因全名 mannose receptor, C type 1
背景介绍 The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. CD206 / MMR is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. [provided by RefSeq, Sep 2015]
生物功能 CD206 / MMR mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.

(Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.

(Microbial infection) Acts as a receptor for Dengue virus envelope protein E.

(Microbial infection) Interacts with Hepatitis B virus envelope protein. [UniProt]
产品亮点 Related products:
CD206 antibodies; CD206 ELISA Kits; CD206 Duos / Panels; Anti-Rabbit IgG secondary antibodies;
Related news:
Tumor-Infiltrating Lymphocytes (TILs)
New antibody panels and duos for Tumor immune microenvironment
Tumor-Infiltrating Lymphocytes (TILs)
研究领域 Immune System antibody; M1/M2/TAM Marker antibody; Macrophage Marker antibody; M2 Macrophage Marker antibody

检测图片 (10) Click the Picture to Zoom In

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat colon tissue stained with ARG22372 anti-CD206 / MMR antibody at 5 µg/ml dilution.

  • ARG22372 anti-CD206 / MMR antibody WB image

    Western blot: 1) Rat brain, 2) Rat kidney, and 3) Mouse brain tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:500 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat skin tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat skin tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:100 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:100 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Pig kidney tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Pig heart tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat kidney tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:200 dilution.

  • ARG22372 anti-CD206 / MMR antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG22372 anti-CD206 / MMR antibody at 1:100 dilution.

文献引用

Abrogation of Toll like receptor 4 (TLR4) mitigates obesity-induced oxidative stress, proinflammation, and insulin resistance through metabolic reprogramming of mitochondria in adipose tissue.

IHC-P / Mouse

Lin Hung-Yu et al.
Antioxid Redox Signal.,  (2020)

publication_link

 

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Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells.

ICC/IF / Human

Yin Xiteng et al.
Cell Oncol (Dordr).,  (2019)

publication_link

 

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