ARG30252

Dengue virus NS1 ELISA Antibody Duo

Datasheet

参考文献2

订购信息

包装

价格 (USD)

1 pair

418

arigo in CHINA:
恩瑞科生物
☎ 400-886-0853,
0571-8708-1890

内含物

货号	内含物名称	宿主克隆性	反应	应用	包装
ARG65661	anti-Dengue virus NS1 antibody [SQab1502]	Mouse mAb	DEN	ELISA, WB	50 μg
ARG65662	anti-Dengue virus NS1 antibody [SQab1503] (Biotin)	Mouse mAb	DEN	ELISA	50 μg

概述

产品描述	Dengue virus NS1 protein is a nonstructural protein which could be secreted and have been developed as diagnostic biomarker for early detection. There are several forms of NS1 including monomer, dimer, and hexamer during infection. Dimeric NS1 can be anchored to cell membranes with glycosyl-phosphatidylinositol (GPI). Hexameric NS1 can be secreted and detected in patients' blood samples (up to 50 μg/mL) or infected cell supernatants (various from ng/mL to μg/mL depend on serotypes and strains). Studies have shown that NS1 could interfere complement activity and prothrombin activation. In addition, NS1 could elicit antibodies which cross-react with host antigens including coagulation factors and molecules expressed in endothelial cells and platelets through molecular mimic. arigo Dengue virus NS1 ELISA Duo could be used to recognize monomer, dimer and hexamer of DENV1/2/3/4 NS1 protein Related news: Best NS1 antibodies in the market Fighting fire with fire: Genetically-engineered mosquitoes as an alternative to fight diseases Exploring Antiviral Immune Response
特异性	Monomer and hexamer of DENV1/2/3/4 NS1 protein
靶点名称	Dengue virus NS1
別名	Dengue virus NS1 ELISA antibody; Dengue virus nonstructural protein 1 ELISA antibody; Dengue virus NS1 antibody; Biotin-conjugated Dengue virus NS1 antibody

属性

存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称	DENV_gp1
全名	Dengue virus nonstructural protein 1 (NS1) ELISA Antibody Duo
背景介绍	Dengue virus NS1 protein is a nonstructural protein which could be secreted and have been developed as diagnostic biomarker for early detection. There are several forms of NS1 including monomer, dimer, and hexamer during infection. Dimeric NS1 can be anchored to cell membranes with glycosyl-phosphatidylinositol (GPI). Hexameric NS1 can be secreted and detected in patients' blood samples (up to 50 μg/mL) or infected cell supernatants (various from ng/mL to μg/mL depend on serotypes and strains). Studies have shown that NS1 could interfere complement activity and prothrombin activation. In addition, NS1 could elicit antibodies which cross-react with host antigens including coagulation factors and molecules expressed in endothelial cells and platelets through molecular mimic.
生物功能	Dengue virus (DENV) non-structural protein 1 (NS1) is involved in virus replication and regulation of the innate immune response. Soluble and membrane-associated NS1 may activate human complement and induce host vascular leakage. This effect might explain the clinical manifestations of dengue hemorrhagic fever and dengue shock syndrome. [Uniprot]
产品亮点	Related products: Dengue Virus antibodies; Dengue Virus ELISA Kits; Dengue Virus Duos / Panels;
研究领域	Microbiology and Infectious Disease antibody

检测图片 (2) Click the Picture to Zoom In

ARG65661 anti-Dengue virus NS1 antibody [SQab1502] & ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) ELISA image

ELISA: 293 cells expressed dengue virus type 2 NS1 protein (major in hexamer) detected by ARG65661 anti-Dengue virus NS1 antibody [SQab1502] as capture antibody (2.5 μg/ml), and ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) (0.5 μg/ml) as detection antibody, followed by incubation with streptavidin-HRP.
ARG65661 anti-Dengue virus NS1 antibody [SQab1502] & ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) ELISA image

ELISA: E. coli expressed recombinant Dengue virus type 1-4 NS1 protein (major in monomer) detected by ARG65661 anti-Dengue virus NS1 antibody [SQab1502] as capture antibody (2.5 μg/ml), and ARG65662 anti-Dengue virus NS1 antibody [SQab1503] (Biotin) (0.5 μg/ml) as detection antibody, followed by incubation with streptavidin-HRP.