circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity

circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity

Circular RNA (circRNA) is a type of covalently closed single-stranded RNA that has been linked to cancer progression. Li et al. reported that circNDUFB2 inhibits growth and metastasis of NSCLC cells. Moreover, circNDUFB2 also triggers type I interferon signaling and activates immune defense response in NSCLC cells.  arigo is proud that our IFN beta, CXCL10, CXCL11, and CCL5 ELISA kits were used to demonstrate that type I interferon signaling is activated by circNDUFB2.


Target Human Mouse Rat
IFN alpha ARG80156 ARG82282 ARG80951
IFN beta ARG81244 ARG82317 ARG81377
CCL5 / RANTES ARG80155 ARG80210 ARG80244
CXCL10 / IP-10 ARG80181 ARG80220  
CXCL11 / I-TAC ARG81444 ARG82060  



Type I interferon signaling


IRF3 antibody [3F10] (ARG56940)


IRF3 pSer396 antibody (ARG57516)


STAT1 antibody (ARG51041)


STAT1 pTyr701 antibody (ARG51548)


STAT2 antibody (ARG66260)

STAT2 pTyr690 antibody (ARG51823)


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Reference: Li et al., (2021) Nat Commun. 12(1):295.

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