ARG83349

arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta 1, PDGF BB, IL6, TNF alpha)

arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA 试剂盒 (TGF beta 1, PDGF BB, IL6, TNF alpha) for ELISA and Mouse

内含物

货号 内含物名称 包装 温度
ARG83349-01 Antibody Coated Microplate 8 X 12 strips 4°C
ARG83349-02 Standard Mixture 3 vials 4°C
ARG83349-03 10X Antibody Conjugate Mixture 1.2 ml ≤ -20 °C
ARG83349-04 40X HRP-Streptavidin Solution 300 μl 4°C
ARG83349-05 Standard / Sample Diluent buffer 35 ml 4°C
ARG83349-06 Antibody Diluent buffer 30 ml 4°C
ARG83349-07 10X Wash Buffer 60 ml 4°C
ARG83349-08 TMB substrate 12 ml 4°C (protect from light)
ARG83349-09 STOP solution 12 ml 4°C
ARG83349-10 Plate sealer 4 adhesive strips Room temperature

概述

产品描述 ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta 1, PDGF BB, IL6, TNF alpha) is an Enzyme Immunoassay kit for the semi-quantification of TGF beta 1, PDGF BB, IL6, TNF alpha in serum, plasma and cell culture supernatant.

See all Multiplex ELISA kits
反应物种 Ms
应用 ELISA
靶点名称 Mouse Fibrotic Marker
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm
灵敏度 TGF beta1: 15.625 pg/mL
PDGF BB: 15.625 pg/mL
IL6: 15.625 pg/mL
TNF alpha: 7.8125 pg/mL
样品类型 Serum, plasma and cell culture supernatant.
标准范围 TGF beta1: 31.25 - 2000 pg/mL
PDGF BB: 31.25 - 2000 pg/mL
IL6: 31.25 - 2000 pg/mL
TNF alpha: 15.625 - 1000 pg/mL
样本量 50 µl

应用说明

检测时间 4.5 hours

属性

形式 96 well
存放说明 Store components at 4°C or -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 TGFB1; PDGFB; IL6; TNF
全名 transforming growth factor, beta 1; platelet-derived growth factor beta polypeptide; interleukin 6; tumor necrosis factor
生物功能 TGF beta 1: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.

PDGF BB: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin.

IL6: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).

TNF alpha: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Up-regulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective.
产品亮点 Related Product:
TGF beta 1 antibodies;
PDGF BB antibodies;
IL6 antibodies;
TNF alpha antibodies;

Related news:
Mouse Fibrotic Marker Multiplex ELISA Kit is launch;

检测图片 (5) Click the Picture to Zoom In

  • Antibodies Coating Pattern In Microtiter Plate of ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha)

  • ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) standard curve image

    ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) results of a typical standard for Mouse TGF beta 1 run with optical density reading at 450 nm.

  • ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) standard curve image

    ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) results of a typical standard for Mouse PDGF BB run with optical density reading at 450 nm.

  • ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) standard curve image

    ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) results of a typical standard for Mouse IL6 run with optical density reading at 450 nm.

  • ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) standard curve image

    ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta1, PDGF BB, IL6, TNF alpha) results of a typical standard for Mouse TNF alpha run with optical density reading at 450 nm.

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ARG83349 arigoPLEX® Mouse Fibrotic Marker Multiplex ELISA Kit (TGF beta 1, PDGF BB, IL6, TNF alpha) User manual download icon Download