ARG10206
anti-beta 2 Microglobulin antibody [D2E9]
anti-beta 2 Microglobulin antibody [D2E9] for ELISA,Flow cytometry,ICC/IF,Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody
概述
| 产品描述 | Mouse Monoclonal antibody [D2E9] recognizes Human beta 2 microglobulin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | D2E9 |
| 同位型 | IgG1, kappa |
| 靶点名称 | beta 2 Microglobulin |
| 抗原物种 | Human |
| 抗原 | Highly purified beta 2 microglobulin from human urine |
| 偶联标记 | Un-conjugated |
| 別名 | Beta-2-microglobulin |
应用说明
| 应用说明 | ELISA: Clone D2E9 can be used as capturer in Sandwich ELISA for B2MG detection. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G affinity purified |
| 缓冲液 | 0.01M PBS (pH 7.2) |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | B2M |
| 全名 | beta-2-microglobulin |
| 背景介绍 | Human beta 2 microglobulin (B2MG) is a component of major histocompatibility complex 1 (MHC1). It is abundant at the surface of lymphocytes and exists at the surface of all cell types except red cells and platelets. B2MG is normally filtered out of blood through glomeruli, but the process is impaired in patients with renal diseases. Elevated B2MG level is implicated with lymphoma, multiple myeloma, renal diseases, viral infections and auto-immune conditions. |
| 生物功能 | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt] |
| 产品亮点 | Related Antibody Duos and Panels: ARG30078 Beta 2 Microglobulin ELISA Antibody Duo Related products: beta 2 Microglobulin antibodies; beta 2 Microglobulin ELISA Kits; beta 2 Microglobulin Duos / Panels; Anti-Mouse IgG secondary antibodies; |
| 研究领域 | Cancer antibody; Cell Biology and Cellular Response antibody |
| 预测分子量 | 14 kDa |
| 翻译后修饰 | Glycation of Ile-21 is observed in long-term hemodialysis patients. |
检测图片 (3) Click the Picture to Zoom In
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ARG10206 anti-beta 2 Microglobulin antibody [D2E9] WB image
Western Blot: 1. B2MG antigen (100 ng) 2. Jurkat cell lysate stained with anti-beta 2 Microglobulin antibody [D2E9] (ARG10206) at 1µg/mL
The molecular weight of B2MG is about 13-14KD -
ARG10206 anti-beta 2 Microglobulin antibody [D2E9] Flow Cytometry image
Flow Cytometry: HeLa cells stained with anti-beta 2 Microglobulin antibody [D2E9] (ARG10206) followed by incubation with fluorescence labelled secondary antibody.
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ARG10206 anti-beta 2 Microglobulin antibody [D2E9] ICC/IF image
Immunofluorescence: Methanol-fixed HeLa cells stained with anti-beta 2 Microglobulin antibody [D2E9] (ARG10206) (green)
