ARG45120
anti-YTHDF2 antibody
anti-YTHDF2 antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes YTHDF2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | YTHDF2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from Human YTHDF2. |
| 偶联标记 | Un-conjugated |
| 別名 | YTHDF2; YTH N6-Methyladenosine RNA Binding Protein F2; HGRG8; NY-REN-2; CAHL; YTH N(6)-Methyladenosine RNA Binding Protein 2; YTH N6-Methyladenosine RNA Binding Protein 2; YTH Domain-Containing Family Protein 2; High-Glucose-Regulated Protein 8; Renal Carcinoma Antigen NY-REN-2; CLL-Associated Antigen KW-14; YTH Domain Family, Member 2; DF2; YTH Domain Family; 9430020E02Rik |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q91YT7 Mouse YTH domain-containing family protein 2 Swiss-port # Q9Y5A9 Human YTH domain-containing family protein 2 |
|---|---|
| 基因名称 | YTHDF2 |
| 全名 | YTH N6-Methyladenosine RNA Binding Protein F2 |
| 背景介绍 | This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012] |
| 生物功能 | May also recognize and bind RNAs modified by C5-methylcytosine (m5C) and act as a regulator of rRNA processing. [Uniprot] |
| 细胞定位 | Cytoplasm, Nucleus. [Uniprot] |
| 产品亮点 | Related news: m6A reader YTHDF2 in mRNA decay and aggresome formation; |
| 预测分子量 | 62 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (6) Click the Picture to Zoom In
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ARG45120 anti-YTHDF2 antibody IHC-P image
Immunohistochemistry: Human rectal cancer stained with ARG45120 anti-YTHDF2 antibody at 2 μg/ml dilution.
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ARG45120 anti-YTHDF2 antibody ICC/IF image
Immunofluorescence: Hep stained with ARG45120 anti-YTHDF2 antibody at 5 μg/ml dilution.
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ARG45120 anti-YTHDF2 antibody WB image
Western blot: K562, Raji stained with ARG45120 anti-YTHDF2 antibody at 0.25 μg/ml dilution.
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ARG45120 anti-YTHDF2 antibody IHC-P image
Immunohistochemistry: Rat intestine stained with ARG45120 anti-YTHDF2 antibody at 2 μg/ml dilution.
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ARG45120 anti-YTHDF2 antibody IHC-P image
Immunohistochemistry: Mouse intestine stained with ARG45120 anti-YTHDF2 antibody at 2 μg/ml dilution.
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ARG45120 anti-YTHDF2 antibody WB image
Western blot: Mouse testis stained with ARG45120 anti-YTHDF2 antibody at 0.25 μg/ml dilution.
