ARG45882
anti-XPG antibody
anti-XPG antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes XPG |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | XPG |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human XPG. |
| 偶联标记 | Un-conjugated |
| 別名 | ERCC Excision Repair 5, Endonuclease; ERCC5; ERCM2; XPG; XPGC; DNA repair protein complementing XP-G cells; EC 3.1.-.-; DNA excision repair protein ERCC-5; Xeroderma pigmentosum group G-complementing protein |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 200 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity chromatography purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -22°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P28715 Human DNA repair protein complementing XP-G cells |
|---|---|
| 基因名称 | ERCC5 |
| 全名 | ERCC Excision Repair 5, Endonuclease |
| 背景介绍 | This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011] |
| 生物功能 | Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. [UniProt] |
| 细胞定位 | Chromosome; Nucleus. [UniProt] |
| 预测分子量 | 133 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (6) Click the Picture to Zoom In
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ARG45882 anti-XPG antibody IHC-P image
Immunohistochemistry: Human colon cancer stained with ARG45882 anti-XPG antibody at 2 μg/ml dilution.
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ARG45882 anti-XPG antibody ICC/IF image
Immunofluorescence: ERCC5 stained with ARG45882 anti-XPG antibody at 5 μg/ml dilution.
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ARG45882 anti-XPG antibody WB image
Western blot: K562 stained with ARG45882 anti-XPG antibody at 0.5 μg/ml dilution.
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ARG45882 anti-XPG antibody FACS image
Flow Cytometry: K562 stained with ARG45882 anti-XPG antibody at 1 µg/10^6 cells dilution.
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ARG45882 anti-XPG antibody WB image
Western blot: C6 stained with ARG45882 anti-XPG antibody at 0.5 μg/ml dilution.
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ARG45882 anti-XPG antibody WB image
Western blot: Neuro-2a stained with ARG45882 anti-XPG antibody at 0.5 μg/ml dilution.
