anti-Synaptophysin antibody [SQab19147]
anti-Synaptophysin antibody [SQab19147] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
|产品描述||Recombinant Rabbit Monoclonal antibody [SQab19147] recognizes Synaptophysin|
|反应物种||Hu, Ms, Rat|
|抗原||Synthetic peptide within aa. 213-313 of Human Synaptophysin.|
|別名||Synaptophysin; MRXSYP; Major synaptic vesicle protein p38; MRX96|
|应用说明||IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C - 25°C) for 30 minutes.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
|纯化||Purification with Protein A.|
|缓冲液||PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.|
|抗菌剂||0.01% Sodium azide|
|稳定剂||40% Glycerol and 0.05% BSA|
|存放说明||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|注意事项||For laboratory research only, not for drug, diagnostic or other use.|
|背景介绍||This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011]|
|生物功能||Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). [UniProt]|
|细胞定位||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome. [UniProt]|
|翻译后修饰||Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. [UniProt]|
检测图片 (2) Click the Picture to Zoom In
ARG66629 anti-Synaptophysin antibody [SQab19147] WB image
Western blot: 20 μg of Mouse brain and Rat brain lysates stained with ARG66629 anti-Synaptophysin antibody [SQab19147] at 1:500 dilution.
ARG66629 anti-Synaptophysin antibody [SQab19147] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human glioma tissue stained with ARG66629 anti-Synaptophysin antibody [SQab19147]. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0).