ARG56230
anti-Synaptophysin antibody
anti-Synaptophysin antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Synaptophysin |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Synaptophysin |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 225-253 (C-terminus) of Human Synaptophysin. |
| 偶联标记 | Un-conjugated |
| 別名 | Synaptophysin; MRXSYP; Major synaptic vesicle protein p38; MRX96 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 阳性对照 | Mouse cerebellum |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SYP |
| 全名 | synaptophysin |
| 背景介绍 | This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011] |
| 生物功能 | Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity). [UniProt] |
| 细胞定位 | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome |
| 预测分子量 | 34 kDa |
| 翻译后修饰 | Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. |
检测图片 (4) Click the Picture to Zoom In
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ARG56230 anti-Synaptophysin antibody ICC/IF image
Immunofluorescence: Human brain cells stained with ARG56230 anti-Synaptophysin antibody (green). DAPI (blue) for nuclear staining.
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ARG56230 anti-Synaptophysin antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human brain tissue stained with ARG56230 anti-Synaptophysin antibody.
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ARG56230 anti-Synaptophysin antibody WB image
Western blot: 35 µg of Mouse cerebellum lysate stained with ARG56230 anti-Synaptophysin antibody.
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ARG56230 anti-Synaptophysin antibody FACS image
Flow Cytometry: Neuro-2a cells stained with ARG56230 anti-Synaptophysin antibody (right histogram) or without primary antibody control (left histogram), followed by incubation with FITC labelled secondary antibody.
