ARG65886
anti-Sp7 / Osterix antibody
anti-Sp7 / Osterix antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat,Rabbit
参考文献2
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Sp7 / Osterix |
|---|---|
| 反应物种 | Hu, Ms, Rat, Rb |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Sp7 / Osterix |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide around aa. 340-400 of Human Sp7 / Osterix. |
| 偶联标记 | Un-conjugated |
| 別名 | Transcription factor Sp7; OI11; osterix; OSX; OI12; Zinc finger protein osterix |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | Aqueous buffered solution, 0.09% Sodium azide, 50% Glycerol and 1% BSA. |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 50% Glycerol and 1% BSA |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SP7 |
| 全名 | Sp7 transcription factor |
| 背景介绍 | This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010] |
| 生物功能 | Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity). [UniProt] |
| 细胞定位 | Nucleus |
| 预测分子量 | 45 kDa |
| 翻译后修饰 | Ubiquitination at leads to proteasomal degradation. SP7 is a short-live protein with an endogenous half-life of approximately 12 hours. |
检测图片 (3) Click the Picture to Zoom In
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ARG65886 anti-Sp7 / Osterix antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Mouse embryo stained with ARG65886 anti-Sp7 / Osterix antibody at 1:200.
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ARG65886 anti-Sp7 / Osterix antibody WB image
Western blot: MC3T3 stained with ARG57829 anti-BMP2 antibody, ARG65886 anti-Sp7 / Osterix antibody, ARG54605 anti-Osteocalcin antibody [OC4-30].
From Liu H et al. Diabetes Metab Syndr Obes. (2023), doi: 10.2147/DMSO.S404392, Fig. 5. C.
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ARG65886 anti-Sp7 / Osterix antibody WB image
Western blot: Mouse spinal cord lysates stained with ARG65886 anti-Sp7 / Osterix antibody at 1:300 overnight at 4°C.
文献引用
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