anti-Slug antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cancer antibody; Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
Rabbit Polyclonal antibody recognizes Slug
|反应物种||Hu, Ms, Rat|
|应用||ICC/IF, IHC-P, WB|
|抗原||KLH-conjugated synthetic peptide corresponding to aa. 98-129 (Center) of Human Slug.|
|別名||Protein snail homolog 2; SNAIL2; WS2D; Neural crest transcription factor Slug; Zinc finger protein SNAI2; SLUG; SLUGH1|
|应用说明||* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.|
|纯化||Purification with Protein G.|
|缓冲液||PBS and 0.09% (W/V) Sodium azide|
|抗菌剂||0.09% (W/V) Sodium azide|
|存放说明||For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.|
|注意事项||For laboratory research only, not for drug, diagnostic or other use.|
|全名||snail family zinc finger 2|
|背景介绍||SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects.|
|研究领域||Cancer antibody; Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody|
|翻译后修饰||GSK3B-mediated phosphorylation results in cytoplasmic localization and degradation.|
检测图片 (3) Click the Picture to Zoom In
ARG55242 anti-Slug antibody ICC/IF image
Immunofluorescence: HepG2 cells stained with ARG55242 anti-Slug antibody (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI (blue) for nuclear staining.
ARG55242 anti-Slug antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human Breast tissue stained with ARG55242 anti-Slug antibody.
ARG55242 anti-Slug antibody WB image
Western blot: 20 µg of Mouse heart lysate stained with ARG55242 anti-Slug antibody at 1:2000 dilution.