ARG55242

anti-Slug antibody

anti-Slug antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Cancer antibody; Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
publication_link 参考文献1

概述

产品描述

Rabbit Polyclonal antibody recognizes Slug

反应物种 Hu, Ms, Rat
预测物种 Bov
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 Slug
抗原物种 Human
抗原 KLH-conjugated synthetic peptide corresponding to aa. 98-129 (Center) of Human Slug.
偶联标记 Un-conjugated
全名 snail family zinc finger 2
別名 Protein snail homolog 2; SNAIL2; WS2D; Neural crest transcription factor Slug; Zinc finger protein SNAI2; SLUG; SLUGH1

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:10 - 1:50
IHC-P1:10 - 1:50
WB1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse heart
预测分子量 30 kDa

属性

形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS and 0.09% (W/V) Sodium azide
抗菌剂 0.09% (W/V) Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 20583 Mouse SNAI2

GeneID: 25554 Rat SNAI2

GeneID: 6591 Human SNAI2

基因名称 SNAI2
基因全名 snail family zinc finger 2
背景介绍 SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects.
研究领域 Cancer antibody; Controls and Markers antibody; Developmental Biology antibody; Gene Regulation antibody; Neuroscience antibody
翻译后修饰 GSK3B-mediated phosphorylation results in cytoplasmic localization and degradation.

检测图片 (3) Click the Picture to Zoom In

  • ARG55242 anti-Slug antibody ICC/IF image

    Immunofluorescence: HepG2 cells stained with ARG55242 anti-Slug antibody (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI (blue) for nuclear staining.

  • ARG55242 anti-Slug antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human Breast tissue stained with ARG55242 anti-Slug antibody.

  • ARG55242 anti-Slug antibody WB image

    Western blot: 20 µg of Mouse heart lysate stained with ARG55242 anti-Slug antibody at 1:2000 dilution.

文献引用

Rap1A promotes esophageal squamous cell carcinoma metastasis through the AKT signaling pathway.

WB / Human

Li Qinfang et al.
Oncol Rep.,  (2019)

publication_link

 

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