ARG40240
anti-Shroom 3 antibody
anti-Shroom 3 antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Shroom 3 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 特异性 | Shroom 3 antibody is human specific. At least four isoforms of Shroom 3 are known to exist; this antibody will detect all four isoforms. Shroom 3 antibody is predicted to not cross-react with other Shroom family members. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Shroom 3 |
| 抗原物种 | Human |
| 抗原 | An 18 amino acid peptide within aa. 850 - 900 of Human Shroom 3. |
| 偶联标记 | Un-conjugated |
| 別名 | ShrmL; Shroom-related protein; hShrmL; Protein Shroom3; SHRM; MSTP013; APXL3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | SK-N-SH cell |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SHROOM3 |
| 全名 | shroom family member 3 |
| 背景介绍 | This gene encodes a PDZ-domain-containing protein that belongs to a family of Shroom-related proteins. This protein may be involved in regulating cell shape in certain tissues. A similar protein in mice is required for proper neurulation. [provided by RefSeq, Jan 2011] |
| 生物功能 | Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers. Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity). [UniProt] |
| 细胞定位 | Cell junction, adherens junction. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin in stress fibers and adherens junctions. [UniProt] |
| 预测分子量 | 217 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40240 anti-Shroom 3 antibody WB image
Western blot: SK-N-SH cell lysate stained with ARG40240 anti-Shroom 3 antibody at 1 µg/ml dilution.
