ARG42952
anti-SDHC antibody
anti-SDHC antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SDHC |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SDHC |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 35-50 of Human SDHC. (KEEMERFWNKNIGSNR) |
| 偶联标记 | Un-conjugated |
| 別名 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; QPs1; Integral membrane protein CII-3; SDH3; CYB560; PGL3; Succinate dehydrogenase complex subunit C; Succinate-ubiquinone oxidoreductase cytochrome B large subunit; QPS1; QPs-1; CYBL |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 19 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q99643 Human Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Swiss-port # Q9CZB0 Mouse Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
|---|---|
| 基因名称 | SDHC |
| 全名 | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
| 背景介绍 | This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2013] |
| 生物功能 | Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 19 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG42952 anti-SDHC antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat gaster tissue stained with ARG42952 anti-SDHC antibody.
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ARG42952 anti-SDHC antibody WB image
Western blot: 50 µg of Rat liver, 50 µg of Mouse liver and 40 µg of HeLa whole cell lysates stained with ARG42952 anti-SDHC antibody at 0.5 µg/ml dilution.
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ARG42952 anti-SDHC antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human gastric cancer tissue stained with ARG42952 anti-SDHC antibody.
