ARG57565
anti-RPGRIP1 antibody
anti-RPGRIP1 antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RPGRIP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RPGRIP1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 530-557 (Center) of Human RPGRIP1. |
| 偶联标记 | Un-conjugated |
| 別名 | CORD13; X-linked retinitis pigmentosa GTPase regulator-interacting protein 1; RPGR-interacting protein 1; RGRIP; LCA6; RPGRIP1d; RGI1; RPGRIP |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HL-60 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q96KN7 Human X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 |
|---|---|
| 基因名称 | RPGRIP1 |
| 全名 | retinitis pigmentosa GTPase regulator interacting protein 1 |
| 背景介绍 | This gene encodes a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells. Mutations in this gene lead to autosomal recessive congenital blindness. [provided by RefSeq, Oct 2008] |
| 生物功能 | May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells. [UniProt] |
| 细胞定位 | Cell projection, cilium. Note=Situated between the axonemal microtubules and the plasma membrane {ECO:0000250|UniProtKB:Q9EPQ2} |
| 预测分子量 | 147 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG57565 anti-RPGRIP1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human breast carcinoma tissue stained with ARG57565 anti-RPGRIP1 antibody.
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ARG57565 anti-RPGRIP1 antibody WB image
Western blot: 35 µg of HL-60 cell lysate stained with ARG57565 anti-RPGRIP1 antibody.
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ARG57565 anti-RPGRIP1 antibody FACS image
Flow Cytometry: MDA-MB-231 cells stained with ARG57565 anti-RPGRIP1 antibody (bottom histogram) or without primary antibody as control (top histogram), followed by incubation with FITC labelled secondary antibody.
