ARG45223
anti-RGS12 antibody
anti-RGS12 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes RGS12 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | RGS12 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human RGS12. |
| 偶联标记 | Un-conjugated |
| 別名 | RGS12; Regulator Of G Protein Signaling 12; Regulator Of G-Protein Signaling 12; Regulator Of G-Protein Signalling 12 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 156 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O08774 Rat Regulator of G-protein signaling 12 Swiss-port # O14924 Human Regulator of G-protein signaling 12 |
|---|---|
| 基因名称 | RGS12 |
| 全名 | Regulator Of G Protein Signaling 12 |
| 背景介绍 | This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.. [UniProt] |
| 细胞定位 | Cell projection; Cytoplasm; Nucleus; Synapse. [UniProt] |
| 预测分子量 | 156 kDa |
| 翻译后修饰 | Isopeptide bond; Methylation; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG45223 anti-RGS12 antibody IHC-P image
Immunohistochemistry: Human rectum adenocarcinoma stained with ARG45223 anti-RGS12 antibody at 2 μg/ml dilution.
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ARG45223 anti-RGS12 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45223 anti-RGS12 antibody at 5 ug/ml dilution.
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ARG45223 anti-RGS12 antibody WB image
Western blot: RT4, SH-SY5Y, and HepG2 stained with ARG45223 anti-RGS12 antibody at 0.5 μg/ml dilution.
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ARG45223 anti-RGS12 antibody IHC-P image
Immunohistochemistry: Rat brian stained with ARG45223 anti-RGS12 antibody at 2 μg/ml dilution.
