ARG58162
anti-Phospholipase C beta 1 antibody
anti-Phospholipase C beta 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Phospholipase C beta 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Phospholipase C beta 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 917-1216 of Human Phospholipase C beta 1 (NP_056007.1). |
| 偶联标记 | Un-conjugated |
| 別名 | EC 3.1.4.11; EIEE12; PLCB1B; PLC154; PLCB1A; Phospholipase C-I; PLC-I; Phosphoinositide phospholipase C-beta-1; Phospholipase C-beta-1; PLC-154; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; PI-PLC; PLC-beta-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | NCI-H460 | ||||||
| 实际分子量 | 145 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PLCB1 |
| 全名 | phospholipase C, beta 1 (phosphoinositide-specific) |
| 背景介绍 | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. [UniProt] |
| 细胞定位 | Nucleus membrane, Cytoplasm. [UniProt] |
| 预测分子量 | 139 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG58162 anti-Phospholipase C beta 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney stained with ARG58162 anti-Phospholipase C beta 1 antibody at 1:100 dilution.
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ARG58162 anti-Phospholipase C beta 1 antibody WB image
Western blot: 25 µg of NCI-H460 cell lysate stained with ARG58162 anti-Phospholipase C beta 1 antibody at 1:1000 dilution.
