ARG45415
anti-PTRF antibody
anti-PTRF antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PTRF |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PTRF |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human PTRF. |
| 偶联标记 | Un-conjugated |
| 別名 | CAVIN1; Caveolae Associated Protein 1; Cavin-1; Polymerase I And Transcript Release Factor; CGL4; PTRF; Congenital Generalized Lipodystrophy 4; Caveolae-Associated Protein 1; RNA Polymerase I And Transcript Release Factor; TTF-I Interacting Peptide 12; FKSG13; CAVIN |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 50-55 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # O54724 Mouse Polymerase I and transcript release factor Swiss-port # Q6NZI2 Human Polymerase I and transcript release factor |
|---|---|
| 基因名称 | CAVIN1 |
| 全名 | Caveolae Associated Protein 1 |
| 背景介绍 | This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009] |
| 生物功能 | Plays an important role in caveolae formation and organization. Essential for the formation of caveolae in all tissues. [UniProt] |
| 细胞定位 | Cell membrane; Cytoplasm; Endoplasmic reticulum; Membrane; Microsome. [UniProt] |
| 预测分子量 | 43 kDa |
| 翻译后修饰 | Acetylation; Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (8) Click the Picture to Zoom In
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ARG45415 anti-PTRF antibody IHC-P image
Immunohistochemistry: Human glioblastoma stained with ARG45415 anti-PTRF antibody at 2 μg/ml dilution.
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ARG45415 anti-PTRF antibody ICC/IF image
Immunofluorescence: Hela stained with ARG45415 anti-PTRF antibody at 5 μg/ml dilution.
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ARG45415 anti-PTRF antibody WB image
Western blot: Hela stained with ARG45415 anti-PTRF antibody at 0.25 μg/ml dilution.
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ARG45415 anti-PTRF antibody FACS image
Flow Cytometry: SiHa stained with ARG45415 anti-PTRF antibody at 1 µg/10^6 cells dilution.
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ARG45415 anti-PTRF antibody IHC-P image
Immunohistochemistry: Rat lung stained with ARG45415 anti-PTRF antibody at 2 μg/ml dilution.
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ARG45415 anti-PTRF antibody WB image
Western blot: Rat heart stained with ARG45415 anti-PTRF antibody at 0.25 μg/ml dilution.
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ARG45415 anti-PTRF antibody IHC-P image
Immunohistochemistry: Mouse lung stained with ARG45415 anti-PTRF antibody at 2 μg/ml dilution.
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ARG45415 anti-PTRF antibody WB image
Western blot: Mouse heart stained with ARG45415 anti-PTRF antibody at 0.25 μg/ml dilution.
