ARG53430
anti-PTHR1 antibody
anti-PTHR1 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PTHR1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PTHR1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to N-terminus of human parathyroid hormone receptor type 1. |
| 偶联标记 | Un-conjugated |
| 別名 | Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor; Parathyroid hormone 1 receptor; PTHR1; PTH/PTHr receptor; PFE; PTHR; PTH1 receptor |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Incubation Time: 10 min at RT. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Parathyroid Gland |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Immunogen affinity purified |
| 缓冲液 | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
| 抗菌剂 | < 0.1% Sodium azide |
| 稳定剂 | 1% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q03431 Human Parathyroid hormone/parathyroid hormone-related peptide receptor |
|---|---|
| 基因名称 | PTH1R |
| 全名 | parathyroid hormone 1 receptor |
| 背景介绍 | The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010] |
| 生物功能 | This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. [UniProt] |
| 细胞定位 | Membrane |
| 研究领域 | Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 66 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG53430 anti-PTHR1 antibody IHC-P image
Immunohistochemistry: Human Parathyroid stained with ARG53430 anti-PTHR1 antibody.
