ARG56485
anti-PTGFR antibody
anti-PTGFR antibody for Western blot and Human,Mouse,Rat,Bovine,Sheep
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PTGFR |
|---|---|
| 反应物种 | Hu, Ms, Rat, Bov, Sheep |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PTGFR |
| 抗原物种 | Mouse |
| 抗原 | Synthetic peptide around the N-terminal cytoplasmic region of Mouse PTGFR. |
| 偶联标记 | Un-conjugated |
| 別名 | FP; Prostanoid FP receptor; Prostaglandin F2-alpha receptor; PGF receptor; PGF2-alpha receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | TBS (pH 7.4) and 5 mg/ml BSA. |
| 稳定剂 | 5 mg/ml BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PTGFR |
| 全名 | prostaglandin F receptor (FP) |
| 背景介绍 | The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost. [UniProt] |
| 预测分子量 | 40 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG56485 anti-PTGFR antibody WB image
Western blot: 1) 20 µg of Bovine cornea, 2) 30 µg of Bovine cornea, 3) 40 µg of Bovine cornea, and 4) 30 µg of Ram seminal vesicle microsomes stained with ARG56485 anti-PTGFR antibody.
