ARG43895
anti-PNPLA6 / NTE antibody
anti-PNPLA6 / NTE antibody for ELISA,Flow cytometry,ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PNPLA6 / NTE |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PNPLA6 / NTE |
| 抗原物种 | Human |
| 抗原 | Human PNPLA6 / NTE recombinant protein |
| 表达系统 | E.coli |
| 偶联标记 | Un-conjugated |
| Protein Full name | Patatin-like phospholipase domain-containing protein 6 |
| 別名 | PNPLA6; Patatin Like Phospholipase Domain Containing 6; NTE; Neuropathy Target Esterase; IPLA2delta; SPG39; Sws; Patatin-Like Phospholipase Domain-Containing Protein 6; EC 3.1.1.5; Patatin-Like Phospholipase Domain Containing 6; NTEMND; BNHS; LNMS; OMCS |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified with Immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PNPLA6 |
| 全名 | Patatin Like Phospholipase Domain Containing 6 |
| 背景介绍 | This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 生物功能 | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. |
| 细胞定位 | Membrane |
| 预测分子量 | 151 kDa |
| 翻译后修饰 | Glycoprotein, Phosphoprotein |
检测图片 (4) Click the Picture to Zoom In
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ARG43895 anti-PNPLA6 / NTE antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG43895 anti-PNPLA6 / NTE antibody at 5 μg/ml dilution.
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ARG43895 anti-PNPLA6 / NTE antibody WB image
Western blot: 293T and SH-SY5Y stained with ARG43895 anti-PNPLA6 / NTE antibody at 0.5 μg/mL dilution.
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ARG43895 anti-PNPLA6 / NTE antibody FACS image
Flow Cytometry: SiHa cells stained with ARG43895 anti-PNPLA6 / NTE antibody (blue) at 1 μg/1x10^6 cells dilution.
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ARG43895 anti-PNPLA6 / NTE antibody WB image
Western blot: HeLa stained with ARG43895 anti-PNPLA6 / NTE antibody at 0.5 μg/mL dilution.
