ARG42234
anti-NPTX2 antibody
anti-NPTX2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NPTX2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NPTX2 |
| 抗原物种 | Human |
| 抗原 | A 16 amino acid peptide within aa. 170-220 of Human NPTX2. |
| 偶联标记 | Un-conjugated |
| 別名 | Neuronal pentraxin II; Neuronal pentraxin-2; NP-II; NARP; NP2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 43 ~ 47 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NPTX2 |
| 全名 | neuronal pentraxin II |
| 背景介绍 | This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009] |
| 生物功能 | Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity). [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 47 kDa |
检测图片 (6) Click the Picture to Zoom In
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG42234 anti-NPTX2 antibody at 5 µg/ml dilution, overnight at 4°C.
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ARG42234 anti-NPTX2 antibody WB image
Western blot: 15 µg of Mouse brain lysate stained with ARG42234 anti-NPTX2 antibody at 0.5 or 1 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: 4% Paraformaldehyde-fixed Mouse brain tissue stained with ARG42234 anti-NPTX2 antibody (red) at 20 µg/ml dilution. DAPI (blue) for nuclear staining.
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human brain tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG42234 anti-NPTX2 antibody at 5 µg/ml dilution, overnight at 4°C.
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: 4% Paraformaldehyde-fixed Human brain tissue stained with ARG42234 anti-NPTX2 antibody at 20 µg/ml dilution.
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ARG42234 anti-NPTX2 antibody WB image
Western blot: 15 µg of 293, A431, A549, CaCo-2, Daudi, HeLa, HepG2, K562, MCF-7, Jurkat, SK-N-SH, THP-1, NIH/3T3 and YB2/0 cell lysates stained with ARG42234 anti-NPTX2 antibody at 2 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.
