ARG45826
anti-NCOA6 antibody
anti-NCOA6 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NCOA6 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NCOA6 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human NCOA6. |
| 偶联标记 | Un-conjugated |
| 別名 | NCOA6; Nuclear Receptor Coactivator 6; RAP250; AIB3; PRIP; TRBP; Nuclear Receptor Coactivator RAP250; KIAA0181; ASC2; NRC; Peroxisome Proliferator-Activated Receptor Interacting Protein; Cancer-Amplified Transcriptional Coactivator ASC-2; Nuclear Receptor-Activating Protein, 250 KDa; Amplified In Breast Cancer Protein 3; Activating Signal Cointegrator-2; PPAR-Interacting Protein; NRC RAP250; Peroxisome Proliferator-Activated Receptor-Interacting Protein; Thyroid Hormone Receptor Binding Protein; Thyroid Hormone Receptor-Binding Protein; Amplified In Breast Cancer-3 Protein; Activating Signal Cointegrator 2; ASC-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 250 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NCOA6 |
| 全名 | Nuclear Receptor Coactivator 6 |
| 背景介绍 | The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. This protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011] |
| 生物功能 | Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 219 kDa |
| 翻译后修饰 | Acetylation; Methylation; Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45826 anti-NCOA6 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45826 anti-NCOA6 antibody at 5 μg/ml dilution.
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ARG45826 anti-NCOA6 antibody WB image
Western blot: Hacat stained with ARG45826 anti-NCOA6 antibody at 0.5 μg/ml dilution.
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ARG45826 anti-NCOA6 antibody FACS image
Flow Cytometry: A431 stained with ARG45826 anti-NCOA6 antibody at 1 µg/10^6 cells dilution.
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ARG45826 anti-NCOA6 antibody WB image
Western blot: Rat testis stained with ARG45826 anti-NCOA6 antibody at 0.5 μg/ml dilution.
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ARG45826 anti-NCOA6 antibody WB image
Western blot: Mouse testis stained with ARG45826 anti-NCOA6 antibody at 0.5 μg/ml dilution.
