ARG45214
anti-Mkl1 / MRTFA antibody
anti-Mkl1 / MRTFA antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Mkl1 / MRTFA |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Mkl1 / MRTFA |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human Mkl1 / MRTFA. |
| 偶联标记 | Un-conjugated |
| 別名 | MRTFA; Myocardin Related Transcription Factor A; MRTF-A; MAL; KIAA1438; BSAC; MKL1; MKL; Megakaryoblastic Leukemia (Translocation) 1; Myocardin-Related Transcription Factor A; Megakaryocytic Acute Leukemia Protein; Megakaryoblastic Leukemia 1 Protein; Basic, SAP And Coiled-Coil Domain; MKL/Myocardin-Like Protein 1; Megakaryocytic Acute Leukemia; Alternative Protein MKL1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 145 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MRTFA |
| 全名 | Myocardin Related Transcription Factor A |
| 背景介绍 | The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| 生物功能 | Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. [UniProt] |
| 细胞定位 | Cytoplasm; Nucleus. [UniProt] |
| 预测分子量 | 98 kDa |
| 翻译后修饰 | Phosphoprotein. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
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ARG45214 anti-Mkl1 / MRTFA antibody ICC/IF image
Immunofluorescence: SiHa stained with ARG45214 anti-Mkl1 / MRTFA antibody at 5 ug/ml dilution.
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ARG45214 anti-Mkl1 / MRTFA antibody WB image
Western blot: Hela stained with ARG45214 anti-Mkl1 / MRTFA antibody at 0.5 μg/ml dilution.
