ARG41416
anti-Lymphotoxin alpha / TNF beta antibody
anti-Lymphotoxin alpha / TNF beta antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Lymphotoxin alpha / TNF beta |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Hm |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Lymphotoxin alpha / TNF beta |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 73-88 of Human TNF beta. (KQNSLLWRANTDRAFL) |
| 偶联标记 | Un-conjugated |
| 別名 | LTA; Lymphotoxin Alpha; TNFSF1; TNFB; LT; Tumor Necrosis Factor Ligand Superfamily Member 1; Lymphotoxin-Alpha; LT-Alpha; TNF-Beta; Lymphotoxin Alpha (TNF Superfamily, Member 1); Tumor Necrosis Factor Ligand 1E; Tumor Necrosis Factor Beta; TNF Superfamily, Member 1; TNF Superfamily Member 1; TNLG1E |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | ~ 17 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Thimerosal and 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LTA |
| 全名 | lymphotoxin alpha |
| 背景介绍 | The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012] |
| 生物功能 | Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo. [UniProt] |
| 细胞定位 | Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane-associated. [UniProt] |
| 预测分子量 | 22 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG41416 anti-Lymphotoxin alpha / TNF beta antibody WB image
Western blot: 10 ng, 5 ng and 2.5 ng of Recombinant Human TNF beta protein stained with ARG41416 anti-Lymphotoxin alpha / TNF beta antibody.
