ARG41093
anti-Ly6G antibody [1A8] (low endotoxin)
anti-Ly6G antibody [1A8] (low endotoxin) for Flow cytometry,Functional study,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation and Mouse
Mouse Inflammatory Cell Marker antibody; Neurophil Marker antibody; Mouse MDSC Marker antibody; Myeloid-derived suppressor cell antibody
概述
| 产品描述 | Low endotoxin Rat Monoclonal antibody [1A8] recognizes Ly6G |
|---|---|
| 反应物种 | Ms |
| 应用 | FACS, FuncSt, IHC-P, IP |
| 特异性 | The antibody specifically reacts with the 21-25 kDa glycophosphatidylinositol-anchored protein known as Ly6G, expressed by the granulocytes from the bone marrow and periphery neutrophils. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | 1A8 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | Ly6G |
| 抗原物种 | Mouse |
| 抗原 | Mouse Ly6G |
| 偶联标记 | Un-conjugated |
| 別名 | Gr1; Gr-1; Ly-6G |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 纯化说明 | Endotoxin level is < 0.01 EU/µg of the protein, as determined by the LAL test. |
| 缓冲液 | PBS (pH 7.2) |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Ly6g |
| 全名 | lymphocyte antigen 6 complex, locus G |
| 背景介绍 | Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses. _x000D_ |
| 细胞定位 | Cell membrane; GPI-anchor. [UniProt] |
| 产品亮点 | Related products: Ly6 antibodies; Ly6 ELISA Kits; Ly6 Duos / Panels; Anti-Rat IgG secondary antibodies; Related news: New antibody panels and duos for Tumor immune microenvironment Exploring Antiviral Immune Response |
| 研究领域 | Mouse Inflammatory Cell Marker antibody; Neurophil Marker antibody; Mouse MDSC Marker antibody; Myeloid-derived suppressor cell antibody |
| 预测分子量 | 12 kDa |
