ARG63034
anti-IgE antibody [4H10]
anti-IgE 抗体 [4H10] for ELISA,Flow cytometry and Human
Immune System antibody
概述
| 产品描述 | Mouse Monoclonal antibody [4H10] recognizes IgE |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS |
| 特异性 | The clone 4H10 reacts with human IgE; it recognizes an epitope different from the ones recognized by BE5 and 4G7 antibodies to IgE. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 4H10 |
| 同位型 | IgG1 |
| 靶点名称 | IgE |
| 抗原物种 | Human |
| 抗原 | Purified human IgE. |
| 偶联标记 | Un-conjugated |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from ascites by precipitation methods and ion exchange chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion. |
| 研究领域 | Immune System antibody |
检测图片 (1) Click the Picture to Zoom In
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ARG63034 anti-IgE antibody [4H10] FACS image
Flow Cytometry: Human peripheral blood cells stained with ARG63034 anti-IgE antibody [4H10], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.
克隆号文献
Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist.
FACS / Human
