ARG66422
anti-IL38 antibody [SQab18124]
anti-IL38 antibody [SQab18124] for ELISA,Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [SQab18124] recognizes IL38 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SQab18124 |
| 同位型 | IgG2b, kappa |
| 靶点名称 | IL38 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human IL38 protein. |
| 偶联标记 | Un-conjugated |
| 別名 | IL1F10; Interleukin 1 Family Member 10; IL-1HY2; IL1-Theta; IL-1F10; FKSG75; Interleukin-1 Receptor Antagonist FKSG75; Interleukin-1 Family Member 10; Family Of Interleukin 1-Theta; Interleukin-1 HY2; Interleukin-38; FIL1 Theta; IL-1 Theta; MGC119832; MGC119833; MGC11983; IL1HY2; IL-38; Interleukin-1 Receptor Antagonist-Like FIL1 Theta; Interleukin 1 Family, Member 10 (Theta); Interleukin 1 Family Member 10 (Theta); IL-1F10 (Canonical Form IL-1F10a); Interleukin-1 Theta; FIL1- Theta; FIL1-Theta; FIL1T; IL38 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Affinity purification with immunogen. |
|---|---|
| 缓冲液 | PBS (pH 7.4) and 0.01% Thimerosal. |
| 抗菌剂 | 0.01% Thimerosal |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL1F10 |
| 全名 | interleukin 1 family, member 10 (theta) |
| 背景介绍 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 17 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG66422 anti-IL38 antibody [SQab18124] ICC/IF image
Immunofluorescence: A549 cells were fixed in 4% PFA, permeabilized with PBS containing 0.1% Triton X-100. Cells were stained with ARG66422 anti-IL38 antibody [SQab18124] (green) at 1:200 dilution and cell nuclei were stained with Hoechst 33342 (blue).
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ARG66422 anti-IL38 antibody [SQab18124] FACS image
Flow Cytometry: A549 cells were stained with ARG66422 anti-IL38 antibody [SQab18124] at 2 µg/ml (red) and without antibody control (black).
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ARG66422 anti-IL38 antibody [SQab18124] WB image
Western blot: 50 ng of Recombinant IL38 protein, 30 µg of 293T and 30 µg of IL38 transfected 293T cell lysates stained with ARG66422 anti-IL38 antibody [SQab18124] at 1:5000 dilution.
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ARG66422 anti-IL38 antibody [SQab18124] ELISA image
ELISA: Titration curve of ARG66422 anti-IL38 antibody [SQab18124]. Red: IL38; Black: BSA (negative control).
