ARG56668
anti-IL1 alpha antibody
anti-IL1 alpha antibody for ELISA,IHC-Frozen sections,Neutralizing,Western blot and Rat
概述
产品描述 | Goat Polyclonal antibody recognizes IL1 alpha |
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反应物种 | Rat |
应用 | ELISA, IHC-Fr, Neut, WB |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | IL1 alpha |
抗原物种 | Rat |
抗原 | E.coli derived Recombinant Rat IL-1α. (MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYVDMDRIH LKAASLNDLQ LEVKFDMYAY SSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKN YFTSAAFPEL LIATKEQSQV HLARGLPSMI DFQIS) |
偶联标记 | Un-conjugated |
別名 | IL-1 alpha; Interleukin-1 alpha; IL1; IL1F1; Hematopoietin-1; IL1-ALPHA; IL-1A |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.2) |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | Il1a |
全名 | interleukin 1 alpha |
背景介绍 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008] |
生物功能 | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. [UniProt] |
产品亮点 | Related products: IL1 alpha antibodies; IL1 alpha ELISA Kits; IL1 alpha recombinant proteins; Anti-Goat IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
预测分子量 | 31 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG56668 anti-IL1 alpha antibody WB image
Western blot: 250 - 0.24 ng of Rat IL-1α stained with ARG56668 anti-IL1 alpha antibody, under reducing conditions.
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ARG56668 anti-IL1 alpha antibody WB image
Western blot: 250 - 0.24 ng of Rat IL-1α stained with ARG56668 anti-IL1 alpha antibody, under non-reducing conditions.
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ARG56668 anti-IL1 alpha antibody standard curve image
Sandwich ELISA: ARG56668 anti-IL1 alpha antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56778 anti-IL1 alpha antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.