ARG63031
anti-Human IgE antibody [BE5] (FITC)
anti-Human IgE 抗体 [BE5] (FITC) for Flow cytometry and Human
Immune System antibody
概述
| 产品描述 | FITC-cojugated Mouse Monoclonal antibody [BE5] recognizes Human IgE |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone BE5 reacts with human IgE; it recognizes an epitope different from the ones recognized by 4G7 and 4H10 antibodies to IgE. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | BE5 |
| 同位型 | IgG1 |
| 靶点名称 | Human IgE |
| 抗原物种 | Human |
| 抗原 | Purified human IgE. |
| 偶联标记 | FITC |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC. |
| 缓冲液 | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion. |
| 研究领域 | Immune System antibody |
检测图片 (2) Click the Picture to Zoom In
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ARG63031 anti-Human IgE antibody [BE5] (FITC) FACS image
Flow Cytometry: Unstimulated normal (heparin-treated) whole blood stained with ARG63031 anti-Human IgE antibody [BE5] (FITC).
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ARG63031 anti-Human IgE antibody [BE5] (FITC) FACS image
Flow Cytometry: Stimulated normal (heparin-treated) whole blood with combination of IL-3 and Goat anti-IgE polyclonal antibody. Staining with ARG63031 anti-Human IgE antibody [BE5] (FITC).
克隆号文献
Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist.
FACS / Human
