ARG55618
anti-HES1 antibody (Center)
anti-HES1 antibody (Center) for Western blot and Mouse
Gene Regulation antibody; Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HES1 (Center) |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HES1 |
| 抗原物种 | Mouse |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 102-137 (Center) of Mouse HES1. |
| 偶联标记 | Un-conjugated |
| 別名 | bHLHb39; Hry; Transcription factor HES-1; Hairy and enhancer of split 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse kidney |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Hes1 |
| 全名 | hairy and enhancer of split 1 (Drosophila) |
| 生物功能 | Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity). [UniProt] |
| 细胞定位 | Nucleus. |
| 研究领域 | Gene Regulation antibody; Neuroscience antibody |
| 预测分子量 | 30 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG55618 anti-HES1 antibody (Center) WB image
Western blot: 20 µg of Mouse kidney lysate stained with ARG55618 anti-HES1 antibody (Center) at 1:1000 dilution.
