ARG58857
anti-Glutaredoxin 1 antibody
anti-Glutaredoxin 1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Glutaredoxin 1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Glutaredoxin 1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 1-106 of Human Glutaredoxin 1 (NP_001112362.1). |
| 偶联标记 | Un-conjugated |
| 別名 | TTase-1; GRX1; Glutaredoxin-1; Thioltransferase-1; GRX |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | NCI-H460 | ||||||||
| 实际分子量 | 12 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GLRX |
| 全名 | glutaredoxin (thioltransferase) |
| 背景介绍 | This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011] |
| 生物功能 | Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. [UniProt] |
| 细胞定位 | Cytoplasm. [UniProt] |
| 预测分子量 | 12 kDa |
检测图片 (3) Click the Picture to Zoom In
-
ARG58857 anti-Glutaredoxin 1 antibody ICC/IF image
Immunofluorescence: MCF-7 cells stained with ARG58857 anti-Glutaredoxin 1 antibody.
-
ARG58857 anti-Glutaredoxin 1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human stomach stained with ARG58857 anti-Glutaredoxin 1 antibody at 1:200 dilution.
-
ARG58857 anti-Glutaredoxin 1 antibody WB image
Western blot: 25 µg of NCI-H460 cell lysate stained with ARG58857 anti-Glutaredoxin 1 antibody at 1:1000 dilution.
