ARG67257
anti-GSDMD (cleaved) antibody
anti-GSDMD (cleaved) antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Monoclonal antibody recognizes GSDMD (cleaved) |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Rat |
| 应用 | ICC/IF, WB |
| 特异性 | ARG67257 detects endogenous levels of Cleaved N-terminal GSDMD. |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 同位型 | IgG, Kappa |
| 靶点名称 | GSDMD (cleaved) |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | GSDMD; Gasdermin D; GSDMDC1; DF5L; Gasdermin Domain-Containing Protein 1; Gasdermin Domain Containing 1; Gasdermin-D; FLJ12150; DFNA5L ; FKSG10 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | 53, 36 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A affinity purified |
| 缓冲液 | PBS, 0.05% Proclin 300, 50% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.05% Proclin 300 |
| 稳定剂 | 50% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GSDMD |
| 全名 | Gasdermin D |
| 背景介绍 | Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
| 生物功能 | Does not bind to unphosphorylated phosphatidylinositol, phosphatidylethanolamine nor phosphatidylcholine. [Uniprot] |
| 细胞定位 | Cell membrane, Cytoplasm, Inflammasome, Membrane, Mitochondrion, Nucleus, Secreted. [Uniprot] |
| 预测分子量 | 53 kDa |
| 翻译后修饰 | Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein, Ubl conjugation. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
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ARG672573 anti-GSDMD (cleaved) antibody ICC/IF image
Immunofluorescence: Un-treated A549 (left) and UV treated A549 (right) stained with ARG672573 anti-GSDMD (cleaved) antibody at 1:200 dilution.
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ARG672573 anti-GSDMD (cleaved) antibody WB image
Western blot: Un-treated THP-1 (left) and LPS treated THP-1 (right) stained with ARG672573 anti-GSDMD (cleaved) antibody at.
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ARG672573 anti-GSDMD (cleaved) antibody WB image
Western blot: Mouse brain stained with ARG672573 anti-GSDMD (cleaved) antibody at 1:200 dilution.
