ARG55808

anti-GRP94 antibody

anti-GRP94 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

概述

产品描述 Rabbit Polyclonal antibody recognizes GRP94
反应物种 Hu, Ms, Rat
应用 ICC/IF, IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 GRP94
抗原物种 Human
抗原 Recombinant protein of Human GRP94 (NP_003290.1)
偶联标记 Un-conjugated
別名 Tumor rejection antigen 1; gp96 homolog; Endoplasmin; 94 kDa glucose-regulated protein; HEL-S-125m; GP96; GRP94; TRA1; HEL35; GRP-94; Heat shock protein 90 kDa beta member 1; ECGP

应用说明

应用建议
应用 推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 NIH/3T3 and HeLa
实际分子量 ~ 96 kDa

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 22027 Mouse HSP90B1

GeneID: 362862 Rat HSP90B1

GeneID: 7184 Human HSP90B1

基因名称 HSP90B1
全名 heat shock protein 90kDa beta (Grp94), member 1
背景介绍 This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]
生物功能 Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. [UniProt]
预测分子量 92 kDa

检测图片 (3) Click the Picture to Zoom In

  • ARG55808 anti-GRP94 antibody ICC/IF image

    Immunofluorescence: NIH/3T3 cells stained with ARG55808 anti-GRP94 antibody at 1:100 dilution.

  • ARG55808 anti-GRP94 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat spleen tissue stained with ARG55808 anti-GRP94 antibody at 1:50 dilution.

  • ARG55808 anti-GRP94 antibody WB image

    Western blot: NIH/3T3 and HeLa cell lysates stained with ARG55808 anti-GRP94 antibody.