ARG45094

anti-GRC5 / PHF2 antibody

anti-GRC5 / PHF2 antibody for Western blot and Human

概述

产品描述 Rabbit Polyclonal antibody recognizes GRC5 / PHF2
反应物种 Hu
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 GRC5 / PHF2
抗原物种 Human
抗原 Synthetic peptide corresponding to residues from an internal region of the 120 kDa PHF protein
偶联标记 Un-conjugated
別名 PHF2; PHD Finger Protein 2; CENP-35; KIAA0662; JHDM1E; KDM7C; Jumonji C Domain-Containing Histone Demethylase 1E; Lysine-Specific Demethylase PHF2; Centromere Protein 35; GRC5; EC 1.14.11.-

应用说明

应用建议
应用 推荐稀释比
WB1:500-1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Antigen Affinity Purified.
缓冲液 PBS, 0.02% NaN3
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 5253 Human PHF2

Swiss-port # O75151 Human Lysine-specific demethylase PHF2

基因名称 PHF2
全名 PHD Finger Protein 2
背景介绍 This gene encodes a protein which contains a zinc finger-like PHD (plant homeodomain) finger, distinct from other classes of zinc finger motifs, and a hydrophobic and highly conserved domain. The PHD finger shows the typical Cys4-His-Cys3 arrangement. PHD finger genes are thought to belong to a diverse group of transcriptional regulators possibly affecting eukaryotic gene expression by influencing chromatin structure. [provided by RefSeq, Jul 2008]
生物功能 Involved in the activation of toll-like receptor 4 (TLR4)-target inflammatory genes in macrophages by catalyzing the demethylation of trimethylated histone H4 lysine 20 (H4K20me3) at the gene promoters. [Uniprot]
细胞定位 Centromere, Chromosome, Kinetochore, Nucleus. [Uniprot]
预测分子量 121 kDa
翻译后修饰 Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot]

检测图片 (1) Click the Picture to Zoom In

  • ARG45094 anti-GRC5 / PHF2 antibody WB image

    Western blot: Human placenta stained with ARG45094 anti-GRC5 / PHF2 antibody.