ARG55324
anti-GLUD1 + GLUD2 antibody
anti-GLUD1 + GLUD2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GLUD1 + GLUD2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 特异性 | This antibody was designed to react C-terminal of GLUD2 protein and it is expected to recognize both GLUD1 and GLUD2 proteins based on sequence homology analysis result |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GLUD1 + GLUD2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to aa. 319-558 of Human GLUD2 (NP_036216.2) |
| 偶联标记 | Un-conjugated |
| 別名 | GDH1; GDH 1; Glutamate dehydrogenase 1, mitochondrial; GDH; GLUD; EC 1.4.1.3; Glutamate dehydrogenase 2, mitochondrial; GLUDP1; EC 1.4.1.3; GDH 2; GDH2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | MCF7 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P49448 Human Glutamate dehydrogenase 2, mitochondrial |
|---|---|
| 基因名称 | GLUD2 |
| 全名 | glutamate dehydrogenase 2 |
| 背景介绍 | The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010] |
| 生物功能 | Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 61 kDa |
| 翻译后修饰 | Stoichiometry shows that ADP-ribosylation occurs in one subunit per catalytically active homohexamer. |
检测图片 (3) Click the Picture to Zoom In
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ARG55324 anti-GLUD1 + GLUD2 antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG55324 anti-GLUD1 + GLUD2 antibody.
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ARG55324 anti-GLUD1 + GLUD2 antibody antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human esophageal cancer tissue stained with ARG55324 anti-GLUD1 + GLUD2 antibody antibody antibody at 1:100 dilution.
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ARG55324 anti-GLUD1 + GLUD2 antibody WB image
Western blot: MCF7 cell lysate stained with ARG55324 anti-GLUD1 + GLUD2 antibody.
