ARG55391
anti-GHSR / Ghrelin Receptor antibody
anti-GHSR / Ghrelin Receptor antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Metabolism antibody; Neuroscience antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GHSR / Ghrelin Receptor |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Pig, Rb |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GHSR / Ghrelin Receptor |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 326-357 (C-terminus) of Human GHSR. |
| 偶联标记 | Un-conjugated |
| 別名 | GHDP; Growth hormone secretagogue receptor type 1; GHS-R; GH-releasing peptide receptor; GHRP; Ghrelin receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse bladder |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q92847 Human Growth hormone secretagogue receptor type 1 Swiss-port # Q99P50 Mouse Growth hormone secretagogue receptor type 1 |
|---|---|
| 基因名称 | GHSR |
| 全名 | growth hormone secretagogue receptor |
| 背景介绍 | This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010] |
| 生物功能 | Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). [UniProt] |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 产品亮点 | Related news: Studying obesity and appetite control by quantifying orexigenic and anorexigenic hormones; |
| 研究领域 | Metabolism antibody; Neuroscience antibody |
| 预测分子量 | 41 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG55391 anti-GHSR / Ghrelin Receptor antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human uterus tissue stained with ARG55391 anti-GHSR / Ghrelin Receptor antibody.
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ARG55391 anti-GHSR / Ghrelin Receptor antibody WB image
Western blot: 35 µg of Mouse bladder lysate stained with ARG55391 anti-GHSR / Ghrelin Receptor antibody.
* Maybe represent the non post-translational modification form of GHSR / Ghrelin Receptor protein.
