ARG56689
anti-GDNF antibody
anti-GDNF antibody for ELISA,Western blot and Human,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GDNF |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | ELISA, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GDNF |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human GDNF. (MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI) |
| 偶联标记 | Un-conjugated |
| 別名 | ATF; Astrocyte-derived trophic factor; HSCR3; hGDNF; Glial cell line-derived neurotrophic factor; HFB1-GDNF; ATF1; ATF2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P39905 Human Glial cell line-derived neurotrophic factor Swiss-port # Q07731 Rat Glial cell line-derived neurotrophic factor |
|---|---|
| 基因名称 | GDNF |
| 全名 | glial cell derived neurotrophic factor |
| 背景介绍 | This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010] |
| 生物功能 | Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. [UniProt] |
| 预测分子量 | 24 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG56689 anti-GDNF antibody WB image
Western blot: 250 - 0.24 ng of Human GDNF stained with ARG56689 anti-GDNF antibody, under reducing conditions.
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ARG56689 anti-GDNF antibody WB image
Western blot: 250 - 0.24 ng of Human GDNF stained with ARG56689 anti-GDNF antibody, under non-reducing conditions.
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ARG56689 anti-GDNF antibody standard curve image
Sandwich ELISA: ARG56689 anti-GDNF antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56798 anti-GDNF antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
