ARG55577
anti-EREG antibody
anti-EREG antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cancer antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes EREG |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EREG |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 137-165 (C-terminus) of Human EREG. |
| 偶联标记 | Un-conjugated |
| 別名 | Proepiregulin; EPR; Ep; ER |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | EREG |
| 全名 | epiregulin |
| 背景介绍 | This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015] |
| 生物功能 | Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis. [UniProt] |
| 细胞定位 | Epiregulin: Secreted, extracellular space. |
| 研究领域 | Cancer antibody; Signaling Transduction antibody |
| 预测分子量 | 19 kDa |
检测图片 (3) Click the Picture to Zoom In
-
ARG55577 anti-EREG antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded colon carcinoma stained with ARG55577 anti-EREG antibody.
-
ARG55577 anti-EREG antibody WB image
Western blot: 20 µg of HepG2 cell lysate stained with ARG55577 anti-EREG antibody at 1:1000 dilution.
-
ARG55577 anti-EREG antibody FACS image
Flow Cytometry: HepG2 cells stained with ARG55577 anti-EREG antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
