ARG45248
anti-EPLIN antibody
anti-EPLIN antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Polyclonal antibody recognizes EPLIN |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | EPLIN |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human EPLIN. |
| 偶联标记 | Un-conjugated |
| 別名 | LIMA1; LIM Domain And Actin Binding 1; EPLIN; Epithelial Protein Lost In Neoplasm Beta; LIM Domain And Actin-Binding Protein 1; SREBP3; Sterol Regulatory Element Binding Protein 3; Epithelial Protein Lost In Neoplasm; LDLCQ8 |
应用说明
| 应用建议 |
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| 实际分子量 | 85 kDa; 100 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9UHB6 Human LIM domain and actin-binding protein 1 |
|---|---|
| 基因名称 | LIMA1 |
| 全名 | LIM Domain And Actin Binding 1 |
| 背景介绍 | This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated. [provided by RefSeq, Aug 2011]. |
| 生物功能 | Actin-binding protein involved in actin cytoskeleton regulation and dynamics. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments. [UniProt] |
| 细胞定位 | Cell junction ; Cell membrane ; Cell projection ; Cytoplasm ; Cytoskeleton ; Membrane. [UniProt] |
| 预测分子量 | 85 kDa |
| 翻译后修饰 | Acetylation ; Phosphoprotein. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
-
ARG45248 anti-EPLIN antibody IHC-P image
Immunohistochemistry: Human lung squamous cell carcinoma stained with ARG45248 anti-EPLIN antibody at 2 μg/ml dilution.
-
ARG45248 anti-EPLIN antibody ICC/IF image
Immunofluorescence: U20S stained with ARG45248 anti-EPLIN antibody at 5 ug/ml dilution.
-
ARG45248 anti-EPLIN antibody WB image
Western blot: HepG2 and T-47D stained with ARG45248 anti-EPLIN antibody at 0.5 μg/ml dilution.
-
ARG45248 anti-EPLIN antibody FACS image
Flow Cytometry: THP-1 stained with ARG45248 anti-EPLIN antibody at 1 µg/10^6 cells dilution.
