anti-DSG1 / Desmoglein 1 antibody

anti-DSG1 / Desmoglein 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat


产品描述 Rabbit Polyclonal antibody recognizes DSG1 / Desmoglein 1
反应物种 Hu, Ms, Rat
应用 IHC-P, WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 DSG1 / Desmoglein 1
抗原物种 Human
抗原 Synthetic peptide of Human DSG1 / Desmoglein 1.
偶联标记 Un-conjugated
別名 PPKS1; Desmoglein-1; SPPK1; DGI; EPKHIA; CDHF4; DG1; Desmosomal glycoprotein 1; DSG; Cadherin family member 4; Pemphigus foliaceus antigen; EPKHE


应用 推荐稀释比
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Human skin
实际分子量 ~ 150 kDa


形式 Liquid
纯化 Affinity purified.
缓冲液 PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 1828 Human DSG1

Swiss-port # Q02413 Human Desmoglein-1

基因名称 DSG1
全名 desmoglein 1
背景介绍 This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
生物功能 Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. [UniProt]
细胞定位 Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome. [UniProt]
预测分子量 114 kDa

检测图片 (2) Click the Picture to Zoom In

  • ARG41648 anti-DSG1 / Desmoglein 1 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human cervix cancer tissue stained with ARG41648 anti-DSG1 / Desmoglein 1 antibody.

  • ARG41648 anti-DSG1 / Desmoglein 1 antibody WB image

    Western blot: Human skin lysate stained with ARG41648 anti-DSG1 / Desmoglein 1 antibody.