ARG59255
anti-DRAM antibody
anti-DRAM antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes DRAM |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | DRAM |
| 抗原物种 | Human |
| 抗原 | A 16 amino acid synthetic peptide within aa. 30 - 80 of Human DRAM. |
| 偶联标记 | Un-conjugated |
| 別名 | DRAM; Damage-regulated autophagy modulator; DNA damage-regulated autophagy modulator protein 1 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | K562 | ||||||
| 实际分子量 | ~ 30 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q8N682 Human DNA damage-regulated autophagy modulator protein 1 Swiss-port # Q9DC58 Mouse DNA damage-regulated autophagy modulator protein 1 |
|---|---|
| 基因名称 | DRAM1 |
| 全名 | DNA-damage regulated autophagy modulator 1 |
| 背景介绍 | This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008] |
| 生物功能 | Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy. [UniProt] |
| 细胞定位 | Lysosome membrane; Multi-pass membrane protein. [UniProt] |
| 预测分子量 | 26 kDa |
检测图片 (5) Click the Picture to Zoom In
-
ARG59255 anti-DRAM antibody IHC image
Immunohistochemistry: Human liver tissue stained with ARG59255 anti-DRAM antibody at 20 µg/ml dilution.
-
ARG59255 anti-DRAM antibody WB image
Western blot: K562 cell lysate stained with ARG59255 anti-DRAM antibody at 0.5, 1 and 2 µg/ml dilution.
-
ARG59255 anti-DRAM antibody IHC image
Immunohistochemistry: Mouse liver tissue stained with ARG59255 anti-DRAM antibody at 20 µg/ml dilution.
-
ARG59255 anti-DRAM antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse liver tissue stained with ARG59255 anti-DRAM antibody at 2 µg/ml dilution.
-
ARG59255 anti-DRAM antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver tissue stained with ARG59255 anti-DRAM antibody at 2.5 µg/ml dilution.
