ARG52865
anti-Chromogranin A antibody
anti-Chromogranin A antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human
Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Chromogranin A |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Chromogranin A |
| 抗原物种 | Human |
| 抗原 | Recombinant protein encoding human chromogranin A. |
| 偶联标记 | Un-conjugated |
| 別名 | Vasostatin II; CGA; Vasostatin I; Pituitary secretory protein I; SP-I; CgA; SL21; Chromogranin-A |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Incubation Time: 10 min at RT. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Pancreas |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Immunogen affinity purified |
| 缓冲液 | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
| 抗菌剂 | < 0.1% Sodium azide |
| 稳定剂 | 1% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 背景介绍 | Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is expressed in carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. |
| 细胞定位 | Cytoplasm |
| 研究领域 | Cancer antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody |
| 预测分子量 | 51 kDa |
| 翻译后修饰 | Sulfated on tyrosine residues and/or contains sulfated glycans. O-glycosylated with core 1 or possibly core 8 glycans. Proteolytic processing gives rise to an additional longer form of catestatin (residues 358-390) which displays a less potent catecholamine release-inhibitory activity (PubMed:10781584). Plasmin-mediated proteolytic processing can give rise to additional shorter and longer forms of catestatin peptides (PubMed:17991725). |
检测图片 (1) Click the Picture to Zoom In
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ARG52865 anti-Chromogranin A antibody IHC-P image
Immunohistochemistry: Human Pancreas stained with ARG52865 anti-Chromogranin A antibody
文献引用
Shigella flexneri Targets Human Colonic Goblet Cells by O Antigen Binding to Sialyl-Tn and Tn Antigens via Glycan-Glycan Interactions.
ICC/IF / Human
