ARG65399

anti-CD90 / Thy 1 antibody [5E10] (azide free)

anti-CD90 / Thy 1 antibody [5E10] (azide free) for CyTOF®-candidate,Flow cytometry,ICC/IF,IHC-Frozen sections,Immunoprecipitation,Western blot and Human,Dog,Primates,Pig

Developmental Biology antibody; Immune System antibody; Neuroscience antibody

概述

产品描述 Azide free Mouse Monoclonal antibody [5E10] recognizes CD90 / Thy 1
反应物种 Hu, Dog, NHuPrm, Pig
应用 CyTOF®-candidate, FACS, ICC/IF, IHC-Fr, IP, WB
特异性 The clone 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
宿主 Mouse
克隆 Monoclonal
克隆号 5E10
同位型 IgG1
靶点名称 CD90 / Thy 1
抗原 HEL erythroleukemia cells.
偶联标记 Un-conjugated
別名 Thy-1 membrane glycoprotein; Thy-1 antigen; CD antigen CD90; CDw90; CD90

应用说明

应用建议
应用 推荐稀释比
CyTOF®-candidateAssay-dependent
FACS1 - 3 µg/ml
ICC/IFAssay-dependent
IHC-Fr5 - 10 µg/ml
IPAssay-dependent
WBAssay-dependent
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Purification with Protein A.
纯化说明 Preserved by filter sterilization.
纯度 > 95% (by SDS-PAGE)
缓冲液 PBS (pH 7.4)
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 7070 Human THY1

Swiss-port # P04216 Human Thy-1 membrane glycoprotein

基因名称 THY1
全名 Thy-1 cell surface antigen
背景介绍 CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.
生物功能 May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. [UniProt]
产品亮点 Related products:
CD90 antibodies; Anti-Mouse IgG secondary antibodies;
Related news:
CyTOF-candidate Antibodies
研究领域 Developmental Biology antibody; Immune System antibody; Neuroscience antibody
预测分子量 18 kDa

克隆号文献

Amniotic fluid-derived mesenchymal stem cells prevent fibrosis and preserve renal function in a preclinical porcine model of kidney transplantation.

Baulier E et al.
Stem Cells Transl Med.,  (2014)

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Immunopathogenic role of TH1 cells in autoimmune diabetes: evidence from a T1 and T2 doubly transgenic non-obese diabetic mouse model.

Hung JT et al.
J Autoimmun.,  (2005)

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Expression of Thy-1 on human hematopoietic progenitor cells.

Craig W et al.
J Exp Med.,  (1993)

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Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.

Mayani H et al.
Blood.,  (1994)

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